Menstrual Cramps

Are You Suffering From Menstrual Cramps? No More!

How many women are suffering

Menstrual pain was reported by 84.1% of women, with 43.1% reporting that pain occurred during every period, and 41% reporting that pain occurred during some periods. From age 15 – 49, nearly 33 million women suffer from menstrual cramp in American, for Avg. 450 cycle of each women’s life, if you have 2 very painful days each cycle, you have 2.5 years in blanket suffering. During your menstrual period, your uterus contracts to help expel its lining. Hormonelike substances (prostaglandins) involved in pain and inflammation trigger the uterine muscle contractions. Higher levels of prostaglandins are associated with more-severe menstrual cramps

 

Underlying Causes of Painful Periods

  • Fibroids
  • Endometriosis
  • Ovarian Cysts
  • Emotions

 

How Ease the Flow works

 1). Decrease the prostaglandins

Moutan Cortex is an elite choice for dealing with painful menstrual symptoms, contains anti-inflammatory properties that inhibit the production of prostaglandins which cast menstrual cramps & hormone imbalances. Also, supporting the body and reducing any cramps and discomfort from studies, is one of the main herbs in Ease the Flow.

 

 2). Balance the HM, improves the mood

 Researchers have shown Biota seeds help metabolize the prostaglandin which casts menstrual cramps & hormone imbalances. It is also used as a sedative, to help disperse anxiety, fear, and insomnia. Other uses are to ease mild heart palpitations, nervous disorders, night sweats, and constipation.

 

Clinically Proven Benefits:

  • Eases menstrual cramps by combating the cramping hormone called prostaglandin*
  • Reduces hormonal acne & bloating*
  • Helps ease back pain & breast soreness*
  • Balances hormones & regulates menstrual cycle*
  • May help with endometriosis & uterine fibroids* 

Menstrual cycles can be incredibly painful and even debilitating. Ease the Flow will help reduce the common side-effects of monthly menstruation, so you don’t have to dread your time of the month!

 

References:

Graham, Lynelle, Mona Boudreaux, and Steve Marsden. “Traditional Chinese Herbal Medicine and Homeopathy in Pain Management.” Pain Management in Veterinary Practice. Wiley-Blackwell, 2013. 171-176.

Mayo, J., and L. Joseph. “Premenstrual syndrome: a natural approach to management.” Appl Nutr Sci Rep 5 (1999): 1-8.

He DY, Dai SM. Anti-inflammatory and immunomodulatory effects of paeonia lactiflora pall., a traditional chinese herbal medicine. Front Pharmacol. 2011;2:10. Published 2011 Feb 25. doi:10.3389/fphar.2011.00010

Yan B, Shen M, Fang J, Wei D, Qin L. Advancement in the chemical analysis of Paeoniae Radix (Shaoyao). J Pharm Biomed Anal. 2018;160:276-288. doi:10.1016/j.jpba.2018.08. 009

Wu L, Yang Y, Mao Z, et al. Processing and Compatibility of Corydalis yanhusuo: Phytochemistry, Pharmacology, Pharmacokinetics, and Safety. Evid Based Complement Alternat Med. 2021;2021:1271953. Published 2021 Dec 30. doi:10.1155/2021/1271953

Pearson W, Orth MW, Karrow NA, Lindinger MI. Effects of simulated digests of Biota orientalis and a dietary nutraceutical on interleukin-1- induced inflammatory responses in cartilage explants. Am J Vet Res. 2008;69(12):1560-1568. doi:10.2460/ajvr.69.12.1560

Chun SC, Jee SY, Lee SG, Park SJ, Lee JR, Kim SC. Anti-inflammatory activity of the methanol extract of moutan cortex in LPS-activated Raw264.7 cells. Evid Based Complement Alternat Med. 2007;4(3):327-333. doi:10.1093/ecam/nel093

 Lin YR, Wu MY, Chiang JH, Yen HR, Yang ST. The utilization of traditional Chinese medicine in patients with dysfunctional uterine bleeding in Taiwan: a nationwide population-based study. BMC Complement Altern Med. 2017;17(1):427. Published 2017 Aug 29. doi:10.1186/s12906-017-1939-1

Angelica essential oil was given to 112 patients for 15-20 days and was 76.79% effective in relieving menstrual pain [Lan Zhou Yi Xue Yuan Xue Bao (Journal of Lanzhou University of Medicine), 1988; 1:36].

Azimi A, Ghaffari SM, Riazi GH, Arab SS, Tavakol MM, Pooyan S. α-Cyperone of Cyperus rotundus is an effective candidate for reduction of inflammation by destabilization of microtubule fibers in brain. J Ethnopharmacol. 2016;194:219-227. doi:10.1016/j.jep.2016.06.058

Ozgoli G, Goli M, Moattar F. Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. J Altern Complement Med. 2009;15(2):129-132. doi:10.1089/acm.2008.0311

Giacosa A, Morazzoni P, Bombardelli E, Riva A, Bianchi Porro G, Rondanelli M. Can nausea and vomiting be treated with ginger extract?. Eur Rev Med Pharmacol Sci. 2015;19(7):1291-1296.

Grzanna R, Lindmark L, Frondoza CG. Ginger–an herbal medicinal product with broad anti-inflammatory actions. J Med Food. 2005;8(2):125-132. doi:10.1089/jmf.2005.8.125

Ruan J, Liu L, Shan X, Xia B, Fu Q. Anti-depressant effects of oil from fructus gardeniae via PKA-CREB-BDNF signaling. Biosci Rep. 2019;39(4):BSR20190141. Published 2019 Apr 26. doi:10.1042/BSR20190141

Bensky D, Gamble A. Chinese Herbal Medicine: Materia Medica. Seattle: Eastland Press, 1993.

McGuffin M, Hobbs C, Upton R, et al. (eds.) American Herbal Products Association’s Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997, p. 55.

Omidvar S, Esmailzadeh S, Baradaran M, Basirat Z. Effect of fennel on pain intensity in dysmenorrhoea: A placebo-controlled trial. Ayu. 2012;33(2):311-313. doi:10.4103/0974-8520.105259

Begum, Monawara, Sumit Das, and Hemanta Kr Sharma. “Menstrual disorders: causes and natural remedies.” J Pharm Chem Biol Sci 4.2 (2016): 307-20.

Salami M, Rahimmalek M, Ehtemam MH. Inhibitory effect of different fennel (Foeniculum vulgare) samples and their phenolic compounds on formation of advanced glycation products and comparison of antimicrobial and antioxidant activities. Food Chem. 2016;213:196-205.

Shalby AB, Hamza AH, Ahmed HH. New insights on the anti-inflammatory effect of some Egyptian plants against renal dysfunction induced by cyclosporine. Eur Rev Med Pharmacol Sci. 2012;16(4):455-461.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392715/

 https://www.mayoclinic.org/diseases-conditions/menstrual-cramps/symptoms-causes/syc-20374938

https://www.hindawi.com/journals/ecam/2007/275192/